The Derby Street Railway was a streetcar operating company in Derby, Connecticut. It began operation in 1888 and at some point before 1900, acquired the Derby & Ansonia Street Railroad Company. In 1900, it was sold to the Connecticut Railway & Lighting Company (CR&L).
From 1906 to 1936, its routes were among those leased by CR&L to The Connecticut Company. In 1936, along with all other CR&L routes, the leases on its routes were voided for nonpayment.